3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester
Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate
CAS: 77779-49-8
Molecular Formula: C12H9ClFNO2
3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester - Names and Identifiers
| Name | Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate |
| Synonyms | Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate ethyl 6-chloro-4-fluoroquinoline-3-carboxylate 4-Chloro-6-fluoroquinoline-3-carboxylic acid ethyl ester 3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester 3-quinolinecarboxylic acid, 4-chloro-6-fluoro-, ethyl ester |
| CAS | 77779-49-8 |
| InChI | InChI=1/C12H9ClFNO2/c1-2-17-12(16)9-6-15-10-4-3-7(14)5-8(10)11(9)13/h3-6H,2H2,1H3 |
3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester - Physico-chemical Properties
| Molecular Formula | C12H9ClFNO2 |
| Molar Mass | 253.66 |
| Density | 1.354 |
| Melting Point | 62-63℃ |
| Boling Point | 332.1°C at 760 mmHg |
| Flash Point | 154.6°C |
| Vapor Presure | 0.00015mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.593 |
| MDL | MFCD00173350 |
3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester - Introduction
Ethyl is an organic compound with the chemical formula C13H9ClFNO2. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to yellow crystal or powdery substance.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is about 77-80°C.
-preservation: should be stored in a cool and dry place, away from fire and oxidant.
Use:
- Ethyl is an important intermediate compound, which has a wide range of applications in the fields of pharmacy, pesticide and organic chemical synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
-At the same time, it can also be used as a reagent in organic synthesis, used to construct quinoline and esterification reactions.
Preparation Method:
- Ethyl can be prepared by a variety of synthetic methods.
-A commonly used method is to chlorinate and fluorinate quinoline and amino acid ester, and then perform esterification reaction to generate Ethyl.
Safety Information:
- Ethyl is generally relatively safe under normal operating conditions, but the following aspects still need to be paid attention:
-It is a chemical and appropriate protective measures should be taken, such as wearing gloves, goggles and protective clothing.
-Avoid inhaling its dust or gas, avoid direct contact with skin and eyes.
-Need to be stored in a sealed container, away from fire and oxidizing agents.
-When using and handling, please refer to the relevant chemical safety manual and consult professional advice.
Nature:
-Appearance: Colorless to yellow crystal or powdery substance.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is about 77-80°C.
-preservation: should be stored in a cool and dry place, away from fire and oxidant.
Use:
- Ethyl is an important intermediate compound, which has a wide range of applications in the fields of pharmacy, pesticide and organic chemical synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
-At the same time, it can also be used as a reagent in organic synthesis, used to construct quinoline and esterification reactions.
Preparation Method:
- Ethyl can be prepared by a variety of synthetic methods.
-A commonly used method is to chlorinate and fluorinate quinoline and amino acid ester, and then perform esterification reaction to generate Ethyl.
Safety Information:
- Ethyl is generally relatively safe under normal operating conditions, but the following aspects still need to be paid attention:
-It is a chemical and appropriate protective measures should be taken, such as wearing gloves, goggles and protective clothing.
-Avoid inhaling its dust or gas, avoid direct contact with skin and eyes.
-Need to be stored in a sealed container, away from fire and oxidizing agents.
-When using and handling, please refer to the relevant chemical safety manual and consult professional advice.
Last Update：2024-04-09 21:11:58
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Product Name: Ethyl 4-chloro-6-fluoroquinoline-3-carboxylate Visit Supplier Webpage Request for quotationCAS: 77779-49-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Ethyl 4-Chloro-6-Fluoroquinoline-3-Carboxylate Visit Supplier Webpage Request for quotation
CAS: 77779-49-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 77779-49-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
3-Quinolinecarboxylicacid, 4-chloro-6-fluoro-, ethyl ester
(4E)-4-(4-{2-[(4-chlorophenyl)sulfanyl]ethoxy}-3-methoxybenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one
赛利替尼
(4E)-4-(4-{2-[(4-chlorophenyl)sulfanyl]ethoxy}-3-methoxybenzylidene)-2-phenyl-1,3-oxazol-5(4H)-one
赛利替尼